First, it can not be combined with or used with alkaline drugs. Because "trichlorfon" is an organophosphorus pesticide preparation, if it meets with alkaline drugs or alkaline substances, it will enhance toxicity, cause livestock poisoning, and even cause death. Sodium bicarbonate, artificial salt, Jianweisan, sodium salts of various sulfonamides, soft soapy water, hard soapy water, lime water, etc. are all alkaline drugs, and should be avoided or used together with "trichlorfon". In addition, if the ordinary water is alkaline hard water, it cannot be used to prepare a trichlorfon solution.
Second, can not exceed the therapeutic dose. Because the therapeutic dose of "trichlorfon" is very close to the poisoning dose, if it is slightly intentional, it will cause poisoning and even death of livestock due to excessive dose. Therefore, in order to ensure the safety of livestock, it is first necessary to accurately determine the weight, and then accurately calculate the amount by weight. Then, what is the internal dose of various livestock "trichlorfon"? The cow is 20-40 mg per kilogram of body weight, the highest dose is 15 grams per time; the horse is 30--50 mg per kilogram of body weight, the highest dose of 1 time. 20 grams; pigs 80-100 mg per kilogram of body weight, 1 time the highest dose is 5 grams; sheep per kilogram of body weight 80--100 mg, 1 time the highest dose is 5 grams; goats are slightly more sensitive than sheep, the amount is less , 50--70 mg per kilogram of body weight, the highest dose of 1 time is 4 grams.
When taking "trichlorfon" orally, it should be formulated with a solution of 1%--3% concentration. The effect of too low concentration is not good, and the side effect will be increased if the concentration is too high. To alleviate the irritation to the stomach of the livestock, it should be mixed with the proper amount of starch. With the application.
Third, poultry can not use the "trichlores" to deworm. Because "trichlorfon" is an organophosphorus preparation, poultry such as chicken, duck, goose and other poultry are particularly sensitive to organophosphorus preparations for three reasons: one is that the organophosphorus preparation can attack the brain of the poultry; the other is that the organophosphorus preparation enters the avian body. It can cause avian neurological disorders; thirdly, the hydrolysis of organic phosphorus preparations by poultry is particularly weak, that is, the natural detoxification ability of organophosphorus preparations is particularly low. Therefore, in addition to chicken knee rickets can be used 0.1% -0.15% of the "trichlorfon" dilute solution to wash the external use of the affected area, absolutely can not use the "trichlorfon" to take the writer's anthelmintic drugs.
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